The Emperor of All Maladies

The Emperor of All Maladies
Author: Siddhartha Mukherjee
Pages: 571
ISBN: 9781439170915
Available:
Release: 2011-08-09
Editor: Simon and Schuster
Language: en

Explanation of the Book:

An assessment of cancer addresses both the courageous battles against the disease and the misperceptions and hubris that have compromised modern understandings, providing coverage of such topics as ancient-world surgeries and the development of present-day treatments. Reprint. Best-selling winner of the Pulitzer Prize. Includes reading-group guide.

The Emperor of All Maladies

The Emperor of All Maladies
Author: Siddhartha Mukherjee
Pages: 592
ISBN: 9781439181713
Available:
Release: 2010-11-16
Editor: Simon and Schuster
Language: en

Explanation of the Book:

Winner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

The Emperor of All Maladies

The Emperor of All Maladies
Author: Siddhartha Mukherjee
Pages: 592
ISBN: 9780007435814
Available:
Release: 2011-02-08
Editor: HarperCollins UK
Language: en

Explanation of the Book:

Winner of the Guardian First Book Award 2011 Winner of the Pulitzer Prize for Non-fiction 2011 Shortlisted for the Wellcome Trust Book Prize Shortlisted for the Duff Cooper Prize

The Laws of Medicine

The Laws of Medicine
Author: Siddhartha Mukherjee
Pages: 96
ISBN: 9781476784854
Available:
Release: 2015-10-13
Editor: Simon and Schuster
Language: en

Explanation of the Book:

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

The Gene

The Gene
Author: Siddhartha Mukherjee
Pages: 608
ISBN: 9781476733531
Available:
Release: 2016-05-17
Editor: Simon and Schuster
Language: en

Explanation of the Book:

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). "Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself." –Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

The First Cell

The First Cell
Author: Azra Raza
Pages: 368
ISBN: 9781541699502
Available:
Release: 2019-10-15
Editor: Basic Books
Language: en

Explanation of the Book:

With the fascinating scholarship of The Emperor of All Maladies and the deeply personal experience of When Breath Becomes Air, a world-class oncologist examines the current state of cancer and its devastating impact on the individuals it affects -- including herself. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must. A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.

Long for This World

Long for This World
Author: Jonathan Weiner
Pages: 320
ISBN: 9780062000217
Available:
Release: 2010-06-22
Editor: Harper Collins
Language: en

Explanation of the Book:

“[A] searching and surprisingly witty look at the scientific odds against tomorrow.” —Timothy Ferris Jonathan Weiner—winner of the Pulitzer Prize, the National Book Critics Circle Award, and the Los Angeles Times Book Prize, and one of the most distinguished popular science writers in America—examines “the strange science of immortality” in Long for This World. A fast-paced, sure-to-astonish scientific adventure from “one of our finest science journalists” (Jonah Lehrer), Weiner’s Long for This World addresses the ageless question, “Is there a secret to eternal youth?” And has it, at long last, been found?

Chasing My Cure

Chasing My Cure
Author: David Fajgenbaum
Pages: 256
ISBN: 9781524799632
Available:
Release: 2021-01-26
Editor: Ballantine Books
Language: en

Explanation of the Book:

LOS ANGELES TIMES AND PUBLISHERS WEEKLY BESTSELLER * The powerful memoir of a young doctor and former college athlete diagnosed with a rare disease who spearheaded the search for a cure--and became a champion for a new approach to medical research. "A wonderful and moving chronicle of a doctor's relentless pursuit, this book serves both patients and physicians in demystifying the science that lies behind medicine."--Siddhartha Mukherjee, New York Times bestselling author of The Emperor of All Maladies and The Gene David Fajgenbaum, a former Georgetown quarterback, was nicknamed the Beast in medical school, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime. Miraculously, Fajgenbaum survived--only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself. More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide. Praise for Chasing My Cure "A page-turning chronicle of living, nearly dying, and discovering what it really means to be invincible in hope."--Angela Duckworth, #1 New York Times bestselling author of Grit "[A] remarkable memoir . . . Fajgenbaum writes lucidly and movingly . . . Fajgenbaum's stirring account of his illness will inspire readers."--Publishers Weekly

Swimming in a Sea of Death

Swimming in a Sea of Death
Author: David Rieff
Pages: 364
ISBN: 9781416554288
Available:
Release: 2008-01-08
Editor: Simon and Schuster
Language: en

Explanation of the Book:

Both a memoir and an investigation, Swimming in a Sea of Death is David Rieff's loving tribute to his mother, the writer Susan Sontag, and her final battle with cancer. Rieff's brave, passionate, and unsparing witness of the last nine months of her life, from her initial diagnosis to her death, is both an intensely personal portrait of the relationship between a mother and a son, and a reflection on what it is like to try to help someone gravely ill in her fight to go on living and, when the time comes, to die with dignity. Rieff offers no easy answers. Instead, his intensely personal book is a meditation on what it means to confront death in our culture. In his most profound work, this brilliant writer confronts the blunt feelings of the survivor -- the guilt, the self-questioning, the sense of not having done enough. And he tries to understand what it means to desire so desperately, as his mother did to the end of her life, to try almost anything in order to go on living. Drawing on his mother's heroic struggle, paying tribute to her doctors' ingenuity and faithfulness, and determined to tell what happened to them all, Swimming in a Sea of Death subtly draws wider lessons that will be of value to others when they find themselves in the same situation.

Life s Edge

Life s Edge
Author: Carl Zimmer
Pages: 368
ISBN: 9780593182727
Available:
Release: 2021-03-09
Editor: Penguin
Language: en

Explanation of the Book:

“Carl Zimmer is one of the best science writers we have today.” —Rebecca Skloot, author of The Immortal Life of Henrietta Lacks We all assume we know what life is, but the more scientists learn about the living world—from protocells to brains, from zygotes to pandemic viruses—the harder they find it is to locate life’s edge. Carl Zimmer investigates one of the biggest questions of all: What is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts—whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead. Life's Edge is an utterly fascinating investigation that no one but one of the most celebrated science writers of our generation could craft. Zimmer journeys through the strange experiments that have attempted to re-create life. Literally hundreds of definitions of what that should look like now exist, but none has yet emerged as an obvious winner. Lists of what living things have in common do not add up to a theory of life. It's never clear why some items on the list are essential and others not. Coronaviruses have altered the course of history, and yet many scientists maintain they are not alive. Chemists are creating droplets that can swarm, sense their environment, and multiply. Have they made life in the lab? Whether he is handling pythons in Alabama or searching for hibernating bats in the Adirondacks, Zimmer revels in astounding examples of life at its most bizarre. He tries his own hand at evolving life in a test tube with unnerving results. Charting the obsession with Dr. Frankenstein's monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.

El Emperador de Todos Los Males The Emperor of All Maladies A Biography of Cancer

El Emperador de Todos Los Males   The Emperor of All Maladies  A Biography of Cancer
Author: Siddhartha Mukherjee
Pages: 712
ISBN: 607314363X
Available:
Release: 2016-12-27
Editor: Unknown
Language: es

Explanation of the Book:

En 2010, siete millones de personas murieron de c�ncer en todo el mundo. Con esta fr�a estad�stica Siddhartha Mukherjee, m�dico e investigador oncol�gico, arranca su amplia y absorbente �biograf�a� de una de las enfermedades m�s extendidas de nuestro tiempo. El emperador de todos los males es una cr�nica completa del c�ncer desde sus or�genes hasta los modernos tratamientos (quimioterapia de diversos tipos, radioterapia y cirug�a, adem�s de la prevenci�n) que han surgido gracias a un siglo de investigaci�n, ensayos y peque�os avances trascendentales en muchos lugares distintos. Este libro es un repaso a la ciencia del c�ncer y a la historia de los tratamientos que le han hecho frente, pero tambi�n es una reflexi�n sobre la enfermedad, la �tica m�dica y las complejas y entrelazadas vidas de los onc�logos y sus pacientes. La empat�a que muestra Mukherjee hacia los enfermos de c�ncer y sus familias, as� como hacia los m�dicos que muy a menudo tan pocas esperanzas les pueden ofrecer, hacen de este libro una historia llena de humanidad de una enfermedad compleja e inasible. Rese�as: �Esta obra deber�a valer a Mukherjee un merecido lugar en el pante�n de los grandes divulgadores de nuestra era, junto a Carl Sagan, Stephen Jay Gould y Stephen Hawking.� The Boston Globe �Una magistral historia de la investigaci�n sobre el c�ncer.� Publishers Weekly ENGLISH DESCRIPTION Winner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane "biography" of cancer--from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with--and perished from--for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer." The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive--and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Cancer

Cancer
Author: Craig A. Almeida,Sheila A. Barry
Pages: 424
ISBN: 9781444357394
Available:
Release: 2011-08-26
Editor: John Wiley & Sons
Language: en

Explanation of the Book:

“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.

Summary Study Guide The Emperor of All Maladies

Summary   Study Guide   The Emperor of All Maladies
Author: Lee Tang
Pages: 102
ISBN: 9780994764072
Available:
Release: 2021
Editor: LMT Press
Language: en

Explanation of the Book:

You will never look at cancer the same way. This book is a summary of "The Emperor of All Maladies: A Biography of Cancer" by Siddhartha Mukherjee. This book chronicles a fascinating "biography" of cancer—from its first documented appearance five thousand years ago through the battles in the 20th century to cure, control, and subdue it, to a new understanding of its biology. It recounts centuries of discoveries, successes, and failures in the cat and mouse battle against cancer, bringing cancer research and cancer biology to the lay public. Read this book to get an informative overview of the evolution of healthcare and health research, in addition to the specific history of cancer. This guide includes: * Book Summary—helps you understand the key concepts. * Online Videos—cover the concepts in more depth. Value-added from this guide: * Save time * Understand key concepts * Expand your knowledge

Guide to Siddhartha Mukherjee s the Emperor of All Maladies

Guide to Siddhartha Mukherjee s the Emperor of All Maladies
Author: Eureka
Pages: 42
ISBN: 1544923287
Available:
Release: 2017-03-24
Editor: Createspace Independent Publishing Platform
Language: en

Explanation of the Book:

PLEASE NOTE: THIS IS A GUIDE TO THE ORIGINAL BOOK. Guide to Siddhartha Mukherjee's The Emperor of All Maladies Preview: Scientist and physician Siddhartha Mukherjee, author of The Emperor of All Maladies, calls his book a biography of cancer rather than simply a history. The author explores a wide range of research, historical accounts, and personal stories in this intensive look at the backstory of cancer. This includes the evolution of cancer's nature, treatment, and the scientific and medical communities' understanding of the disease as well as the support of the public and politicians in the crucial fight to find a cure... Inside this companion: -Overview of the book -Important People -Key Insights -Analysis of Key Insights

The Best American Science and Nature Writing 2013

The Best American Science and Nature Writing 2013
Author: Siddhartha Mukherjee,Tim Folger
Pages: 367
ISBN: 9780544003484
Available:
Release: 2013-10-08
Editor: Houghton Mifflin Harcourt
Language: en

Explanation of the Book:

Twenty-seven of America’s best science and nature essays of 2013, selected by the author of The Emperor of All Maladies and the #1 New York Times bestseller, The Gene. Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields. The Best American Science & Nature Writing 2013 includes: “The T-Cell Army” by Jerome Groopman “The Artificial Leaf” by David Owen “The Life of Pi, and Other Infinities” by Natalie Angier “Altered States” by Oliver Sacks “Recall of the Wild” by Elizabeth Kolbert “Super Humanity” by Robert M. Sapolsky “Can a Jellyfish Unlock the Secret of Immortality?” by Nathaniel Rich Contributors also include: J. B. Mackinnon · Benjamin Hale · Tim Zimmermann · David Deutsch and Artur Ekert · Michael Moyer · Sylvia A. Earle · John Pavlus · Michelle Nijhuis · Rick Bass · Michael Specter · Alan Lightman · David Quammen · Keith Gessen · Steven Weinberg · Gareth Cook · Katherine Harmon · Stephen Marche · Mark Bowden · Kevin Dutton

A Cancer in the Family

A Cancer in the Family
Author: Theodora Ross, MD, PhD,Siddhartha Mukherjee
Pages: 288
ISBN: 9780698197893
Available:
Release: 2016-02-02
Editor: Penguin
Language: en

Explanation of the Book:

A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

The Emperor of All Maladies

The Emperor of All Maladies
Author: Siddhartha Mukherjee
Pages: 329
ISBN: 0007447876
Available:
Release: 2010
Editor: Unknown
Language: en

Explanation of the Book:

A "biography" of cancer from its origins to the epic battle to cure, control, and conquer it. A combination of medical history, cutting-edge science, and narrative journalism that transforms the listener's understanding of cancer and much of the world around them. The author provides a glimpse into the future of cancer treatments and offers a bold new perspective on the way doctors, scientists, philosophers, and lay people have observed and understood the human body for millennia.

The Emperor of All Maladies

The Emperor of All Maladies
Author: Lee Tang
Pages: 329
ISBN: OCLC:1230140427
Available:
Release: 2017
Editor: Unknown
Language: en

Explanation of the Book:

My Dear I Wanted to Tell You

My Dear I Wanted to Tell You
Author: Louisa Young
Pages: 336
ISBN: 9781443408318
Available:
Release: 2011-05-31
Editor: HarperCollins Canada
Language: en

Explanation of the Book:

On the day in 1907 that eleven-year-old Riley Purefoy meets Nadine Waveney, he notes the difference between their two families—his, working class; hers, wealthier and artistic—and vows to better himself. Nadine’s mother likes Riley as a young boy, but when, a few years later, she detects the romance budding between the two, she fears for her daughter’s future. Angry and humiliated, Riley enlists at the nearest recruiting station during the febrile first weeks of the First World War and ships for France. While Riley and his commanding officer, Peter Locke, fight for their country, their sanity and their survival in the trenches of Flanders, every day Peter’s wife, Julia, undertakes ever more neurotic rituals to prepare for her beloved husband’s return. Then when he does return on leave, she finds him distant, changed and damaged, beyond the scope of anything she can do. Nadine, only eighteen when the war starts, above all wants to make promises—but how can she when her future with Riley is completely out of her hands? Youthful passion is on their side, but their bond is tested by a terrible injury, and even more so by the imperfect rehabilitation that follows.

The Two Kinds of Decay

The Two Kinds of Decay
Author: Sarah Manguso
Pages: 192
ISBN: 9781429940986
Available:
Release: 2009-05-26
Editor: Farrar, Straus and Giroux
Language: en

Explanation of the Book:

A Spare and Unsparing Look at Affliction and Recovery that Heralds a Stunning New Voice The events that began in 1995 might keep happening to me as long as things can happen to me. Think of deep space, through which heavenly bodies fly forever. They fly until they change into new forms, simpler forms, with ever fewer qualities and increasingly beautiful names. There are names for things in spacetime that are nothing, for things that are less than nothing. White dwarfs, red giants, black holes, singularities. But even then, in their less-than-nothing state, they keep happening. At twenty-one, just starting to comprehend the puzzles of adulthood, Sarah Manguso was faced with another: a wildly unpredictable disease that appeared suddenly and tore through her twenties, vanishing and then returning, paralyzing her for weeks at a time, programming her first to expect nothing from life and then, furiously, to expect everything. In this captivating story, Manguso recalls her nine-year struggle: arduous blood cleansings, collapsed veins, multiple chest catheters, the deaths of friends and strangers, addiction, depression, and, worst of all for a writer, the trite metaphors that accompany prolonged illness. A book of tremendous grace and self-awareness, The Two Kinds of Decay transcends the very notion of what an illness story can and should be.