The Gene the Clinic and the Family

The Gene  the Clinic  and the Family
Author: Joanna Latimer
Pages: 256
ISBN: 0415699282
Available:
Release: 2013
Editor: Unknown
Language: en

Explanation of the Book:

While some theorists argue that medicine is caught in a relentless process of 'geneticization' and others offer a thesis of biomedicalization, there is still little research that explores how these effects are accomplished in practice. Joanna Latimer, whose groundbreaking ethnography on acute medicine gave us the social science classic The Conduct of Care, moves her focus from the bedside to the clinic in this in-depth study of genetic medicine. Against current thinking that proselytises the rise of laboratory science, Professor Latimer shows how the genetic clinic is at the heart of the revolution in the new genetics. Tracing how work on the abnormal in an embryonic genetic science, dysmorphology, is changing our thinking about the normal, The Gene, the Clinic, and the Family charts new understandings about family, procreation and choice. Far from medicine experiencing the much-proclaimed 'death of the clinic', this book shows how medicine is both reasserting its status as a science and revitalising its dominance over society, not only for now but for societies in the future. This book will appeal to students, scholars and professionals interested in medical sociology, science and technology studies, the anthropology of science, medical science and genetics, as well as genetic counselling.

The Gene the Clinic and the Family

The Gene  the Clinic  and the Family
Author: Joanna Latimer
Pages: 238
ISBN: 9781135070144
Available:
Release: 2013-07-04
Editor: Routledge
Language: en

Explanation of the Book:

While some theorists argue that medicine is caught in a relentless process of ‘geneticization’ and others offer a thesis of biomedicalization, there is still little research that explores how these effects are accomplished in practice. Joanna Latimer, whose groundbreaking ethnography on acute medicine gave us the social science classic The Conduct of Care, moves her focus from the bedside to the clinic in this in-depth study of genetic medicine. Against current thinking that proselytises the rise of laboratory science, Professor Latimer shows how the genetic clinic is at the heart of the revolution in the new genetics. Tracing how work on the abnormal in an embryonic genetic science, dysmorphology, is changing our thinking about the normal, The Gene, the Clinic, and the Family charts new understandings about family, procreation and choice. Far from medicine experiencing the much-proclaimed ‘death of the clinic’, this book shows how medicine is both reasserting its status as a science and revitalising its dominance over society, not only for now but for societies in the future. This book will appeal to students, scholars and professionals interested in medical sociology, science and technology studies, the anthropology of science, medical science and genetics, as well as genetic counselling.

The Gene the Clinic and the Family

The Gene  the Clinic  and the Family
Author: Joanna Latimer
Pages: 238
ISBN: 9781135070137
Available:
Release: 2013-07-04
Editor: Routledge
Language: en

Explanation of the Book:

While some theorists argue that medicine is caught in a relentless process of ‘geneticization’ and others offer a thesis of biomedicalization, there is still little research that explores how these effects are accomplished in practice. Joanna Latimer, whose groundbreaking ethnography on acute medicine gave us the social science classic The Conduct of Care, moves her focus from the bedside to the clinic in this in-depth study of genetic medicine. Against current thinking that proselytises the rise of laboratory science, Professor Latimer shows how the genetic clinic is at the heart of the revolution in the new genetics. Tracing how work on the abnormal in an embryonic genetic science, dysmorphology, is changing our thinking about the normal, The Gene, the Clinic, and the Family charts new understandings about family, procreation and choice. Far from medicine experiencing the much-proclaimed ‘death of the clinic’, this book shows how medicine is both reasserting its status as a science and revitalising its dominance over society, not only for now but for societies in the future. This book will appeal to students, scholars and professionals interested in medical sociology, science and technology studies, the anthropology of science, medical science and genetics, as well as genetic counselling.

Tangled Diagnoses

Tangled Diagnoses
Author: Ilana Löwy
Pages: 352
ISBN: 9780226534268
Available:
Release: 2018-04-19
Editor: University of Chicago Press
Language: en

Explanation of the Book:

Since the late nineteenth century, medicine has sought to foster the birth of healthy children by attending to the bodies of pregnant women, through what we have come to call prenatal care. Women, and not their unborn children, were the initial focus of that medical attention, but prenatal diagnosis in its present form, which couples scrutiny of the fetus with the option to terminate pregnancy, came into being in the early 1970s. Tangled Diagnoses examines the multiple consequences of the widespread diffusion of this medical innovation. Prenatal testing, Ilana Löwy argues, has become mainly a risk-management technology—the goal of which is to prevent inborn impairments, ideally through the development of efficient therapies but in practice mainly through the prevention of the birth of children with such impairments. Using scholarship, interviews, and direct observation in France and Brazil of two groups of professionals who play an especially important role in the production of knowledge about fetal development—fetopathologists and clinical geneticists—to expose the real-life dilemmas prenatal testing creates, this book will be of interest to anyone concerned with the sociopolitical conditions of biomedical innovation, the politics of women’s bodies, disability, and the ethics of modern medicine.

Understanding Genetics

Understanding Genetics
Author: Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services
Pages: 100
ISBN: 9780982162217
Available:
Release: 2009
Editor: Lulu.com
Language: en

Explanation of the Book:

The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. At the end of each section, a list of references is provided for additional information. Appendices can be copied for reference and offered to patients. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.

The Practical Guide to the Genetic Family History

The Practical Guide to the Genetic Family History
Author: Robin L. Bennett
Pages: 384
ISBN: 9781118209813
Available:
Release: 2011-09-20
Editor: John Wiley & Sons
Language: en

Explanation of the Book:

HELPS YOU DEVELOP AND ASSESS PEDIGREES TO MAKE DIAGNOSES, EVALUATE RISK, AND COUNSEL PATIENTS The Second Edition of The Practical Guide to the Genetic Family History not only shows how to take a medical-family history and record a pedigree, but also explains why each bit of information gathered is important. It provides essential support in diagnosing conditions with a genetic component. Moreover, it aids in recommending genetic testing, referring patients for genetic counseling, determining patterns of inheritance, calculating risk of disease, making decisions for medical management and surveillance, and informing and educating patients. Based on the author's twenty-five years as a genetic counselor, the book also helps readers deal with the psychological, social, cultural, and ethical problems that arise in gathering a medical-family history and sharing findings with patients. Featuring a new Foreword by Arno Motulsky, widely recognized as the founder of medical genetics, and completely updated to reflect the most recent findings in genetic medicine, this Second Edition presents the latest information and methods for preparing and assessing a pedigree, including: Value and utility of a thorough medical-family history Directed questions to ask when developing a medical-family history for specific disease conditions Use of pedigrees to identify individuals with an increased susceptibility to cancer Verification of family medical information Special considerations when adoptions or gamete donors are involved Ethical issues that may arise in recording a pedigree Throughout the book, clinical examples based on hypothetical families illustrate key concepts, helping readers understand how real issues present themselves and how they can be resolved. This book will enable all healthcare providers, including physicians, nurses, medical social workers, and physician assistants, as well as genetic counselors, to take full advantage of the pedigree as a primary tool for making a genetic risk assessment and providing counseling for patients and their families.

Practical Paediatric Problems

Practical Paediatric Problems
Author: Jim Beattie,Robert Carachi
Pages: 652
ISBN: 9781444114621
Available:
Release: 2005-08-26
Editor: CRC Press
Language: en

Explanation of the Book:

This innovative text, modelled on the current RCPCH syllabus for paediatric training, provides all the information that the senior house officer and specialist registrar in paediatrics will need during training and when preparing for the MRCPCH examination. A series of chapters discussing general principles in paediatric medicine is followed by a s

The Practical Guide to the Genetic Family History

The Practical Guide to the Genetic Family History
Author: Robin L. Bennett
Pages: 272
ISBN: 9780471459149
Available:
Release: 2004-04-07
Editor: John Wiley & Sons
Language: en

Explanation of the Book:

The Practical Guide to The Genetic Family History Robin L. BennettCompiling the most recent genetic developments in medicalspecialties, The Practical Guide to the Genetic Family History is avaluable resource which outlines the proper methods for taking andrecording a patient's family medical history, allowing primary carephysicians to be more efficient in diagnosing conditions withpotential genetic components. With genetic screening forms, anoverview of directed questions, pedigree nomenclature, andoutlining common approaches used, genetic counselor Robin L.Bennett provides readers with the basic foundation in humangenetics necessary to recognize inherited disorders and familialdisease susceptibility in patients. As the only guide which isgeared for the physician in this field, The Practical Guide to theGenetic Family History includes remarks by renowned medicalgeneticist Arno Motulsky, as well as information on structuring anaccurate pedigree and its components, including: * Using a pedigree to identify individuals with an increasedsusceptibility to cancer * Family history, adoption, and their challenges * The connection between the pedigree and assisted reproductivetechnologies * Making referrals for genetic services * Neurological and neuromuscular conditions * Tables covering hearing loss, mental retardation, dementia, andseizures * Five case studies of genetics in practice An essential reference for genetics clinics, medical geneticists,and counselors, The Practical Guide to the Genetic Family Historyis also an invaluable aid for both primary care and specialistphysicians who need an up-to-date reference that emphasizes boththe science and art of modern clinical genetics.

Breast Cancer Gene Research and Medical Practices

Breast Cancer Gene Research and Medical Practices
Author: Sahra Gibbon,Galen Joseph,Jessica Mozersky,Andrea zur Nieden,Sonja Palfner
Pages: 248
ISBN: 9781135925451
Available:
Release: 2014-03-05
Editor: Routledge
Language: en

Explanation of the Book:

The discovery of the two inherited susceptibility genes BRCA1 and BRCA2 in the mid-1990s created the possibility of predictive genetic testing and led to the establishment of specific medical programmes for those at high risk of developing breast cancer in the UK, US and Europe. In the intervening fifteen years, the medical institutionalisation of these knowledge-practices and accompanying medical techniques for assessing and managing risk have advanced at a rapid pace across multiple national and transnational arenas, whilst also themselves constituting a highly mobile and shifting terrain. This unique edited collection brings together cross-disciplinary social science research to present a broad global comparative understanding of the implications of BRCA gene research and medical practices. With a focus on time-economies that unfold locally, nationally and transnationally (including in Brazil, Canada, France, Germany, India, Italy, the UK and the USA), the essays in this volume facilitate a re-reading of concepts such as prevention, kinship and heredity, and together offer a unique, timely and comparative perspective on these developments. The book provides a coherent structure for examining the diversity of practices and discourses that surround developments linked to BRCA genetics, and to the evolving field of genetics more broadly. It will be of interest to students and scholars of anthropology, sociology, history of science, STS, public health and bioethics. Chapter 8 of this book is freely available as a downloadable Open Access PDF at www.tandfebooks.com/openaccess. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license.

The Meanings of the Gene

The Meanings of the Gene
Author: Celeste Michelle Condit
Pages: 325
ISBN: 0299163644
Available:
Release: 1999
Editor: Univ of Wisconsin Press
Language: en

Explanation of the Book:

The Meanings of the Gene is a compelling look at societal hopes and fears about genetics in the course of the twentieth century. The work of scientists and doctors in advancing genetic research and its applications has been accompanied by plenty of discussion in the popular press—from Good Housekeeping and Forbes to Ms. and the Congressional Record—about such topics as eugenics, sterilization, DNA, genetic counseling, and sex selection. By demonstrating the role of rhetoric and ideology in public discussions about genetics, Condit raises the controversial question, Who shapes decisions about genetic research and its consequences for humans—scientists, or the public? Analyzing hundreds of stories from American magazines—and, later, television news—from the 1910s to the 1990s, Condit identifies three central and enduring public worries about genetics: that genes are deterministic arbiters of human fate; that genetics research can be used for discriminatory ends; and that advances in genetics encourage perfectionistic thinking about our children. Other key public concerns that Condit highlights are the complexity of genetic decision-making and potential for invasion of privacy; conflict over the human genetic code and experimentation with DNA; and family genetics and reproductive decisions. Her analysis reveals a persistent debate in the popular media between themes of genetic determinism (such as eugenics) and more egalitarian views that place genes within the complexity of biological and social life. The Meanings of the Gene offers an insightful view of our continuing efforts to grapple with our biological natures and to define what it means, and will mean in the future, to be human.

Genetics and Precision Medicine An issue of Medical Clinics of North America EBook

Genetics and Precision Medicine An issue of Medical Clinics of North America EBook
Author: Howard P. Levy
Pages: 329
ISBN: 9780323696265
Available:
Release: 2019-10-08
Editor: Elsevier Health Sciences
Language: en

Explanation of the Book:

This issue of Medical Clinics of North America, guest edited by Dr. Howard P. Levy, is devoted to Genetics and Precision Medicine. Articles in this important issue include: Family History in Genetics and Precision Medicine; Genetic Testing: Who, What, When and Why; Test Result Disclosure and When to Consult a Geneticist or Genetic Counselor; Patient Engagement to Inform a Large-scale Population Sequencing Program; Pharmacogenetics: Prescribing Precisely; DNA Testing for Early Cancer Diagnosis; Breast Cancer: BRCA and Beyond; Colon Cancer and Other GI Cancers; Neurofibromatosis and Related Disorders; Marfan, Loeys Dietz, and Other Syndromes Causing Arterial Fragility; Ehlers Danlos Syndromes and Related Disorders of Connective Tissue; Parkinson, Alzheimer, and Other Neuropsychiatric Diseases; Genetic Neurologic and Neuromuscular Disorders; and Polycystic Kidney Disease and Other Genetic Kidney Disorders. A CME program is also available for this title.

Genetic Hearing Loss

Genetic Hearing Loss
Author: Patrick J. Willems
Pages: 406
ISBN: 9780824756888
Available:
Release: 2003-10-17
Editor: CRC Press
Language: en

Explanation of the Book:

Heredity, either alone or in combination with environmental factors, is the most prominent underlying cause of hearing impairment. Thanks in large part to positional cloning techniques, scientists have identified nearly 100 gene loci implicated in hearing loss since 1995-an extraordinarily rapid rate of gene identification. Genetic Hearing Loss branches into syndromic and nonsyndromic categorical directions in its coverage of the genetics behind hearing loss. Authored by 60 internationally recognized researchers, the book describes the normal development of the ear, updates the classification and epidemiology of hearing loss, and surveys the usage of audiometric tests and diagnostic medical examinations.

Breast Cancer Genes and the Gendering of Knowledge

Breast Cancer Genes and the Gendering of Knowledge
Author: Sahra Gibbon
Pages: 221
ISBN: 9780230626553
Available:
Release: 2006-12-14
Editor: Springer
Language: en

Explanation of the Book:

The book examines the social and cultural context of new genetic knowledge associated with breast cancer. It looks at how this knowledge and technologies are used and received in two contrasting social arenas - cancer genetic clinics and a breast cancer research charity.

Genetics and Sleep An Issue of Sleep Medicine Clinics E Book

Genetics and Sleep  An Issue of Sleep Medicine Clinics   E Book
Author: Allan Pack
Pages: 144
ISBN: 9781455712007
Available:
Release: 2011-07-22
Editor: Elsevier Health Sciences
Language: en

Explanation of the Book:

This issue describes in detail the most current thinking on the way genes affect and determine sleep patterns, behaviors, disorders and needs. Sleep researchers continue to study genetic markers that may someday lead to a personalized approach to treatment of sleep disorders. The genetics of restless legs syndrome, narcolepsy, circadian rhythm disorders, obstructive sleep apnea, parasomnias, and insomnia are discussed. A solid understanding of the role genetics and molecular biology play in sleep will aid clinicians in diagnosing and treating these disorders, as well as advising their patients.

Technologies for Prenatal Diagnosis and Assessment of Genetic Disorders

Technologies for Prenatal Diagnosis and Assessment of Genetic Disorders
Author: Fan Jin,Yueqiu Tan,Evica Rajcan-Separovic,Peter C. K. Leung
Pages: 329
ISBN: 9782889637393
Available:
Release: 2020-06-22
Editor: Frontiers Media SA
Language: en

Explanation of the Book:

Birth defects are one of the major public health concerns in the world, as they cause approximately 20% of infant deaths. Genetic disorders, including chromosome abnormalities and single gene disorders, are the most common causes of birth defects for which there is no efficient treatment. Prenatal genetic screening and diagnosis allow early identification of affected conceptuses and facilitates reproduction planning or counseling. Molecular technologies have developed rapidly in recent years and have been widely used in screening and diagnosis of genetic disorders at all stages of prenatal development (e.g. pre-implantation, embryonic and fetal). However, their performance still needs to be validated and assessed as the balance between their advantages and disadvantages need to be discussed. With the ability to detect copy number variations (CNVs), polyploidy, uniparental disomy and maternal cell contamination, SNP-based chromosomal microarray analysis (CMA) is showing the unique importance in diagnosing chromosomal abnormalities. The interpretation of CNVs remains a challenge; however, ultrasound and biochemical screening improve the diagnosis of fetal chromosomal abnormalities. Whole exome sequencing (WES) and whole genome sequencing (WGS) play increasingly significant roles in prenatal and carrier screening for genetic disorders. NGS-based non-invasive prenatal screening (NIPS) is now widely used for detecting common autosomal aneuploidies and has shown the potential of detecting microdeletions and microduplications. However, further investigations of the sensitivity and accuracy are required and large-scale data is necessary to evaluate the performance and clinical applications of current and new methods. Recently, reports of application of newer technologies in prenatal setting became available. Examples include third generation sequencing (reading the nucleotide sequences at the single molecule level), digital PCR (used for direct quantification of DNA) and cell-based NIPT. In the followed listed papers, the authors showed their successful experiences in identifying novel mutation, detecting low-level mosaicism or de novo mutations limited in germline cells, investigating the association of the CNVs with specific phenotypic alterations by using WES, CMA, digital PCR and some other new-developed molecular techniques. More interesting, the authors also presented a report about the evaluation of diagnostic yield in fetal WES, which suggested a new tendency to apply WES or WGS directly for prenatal diagnosis. We believed that the efficiency of scanning causative mutations and prenatal or preimplantion genetic diagnosis for genetic disorders will further improved based on the technologies of whole genomic sequencing with further improved output and resolution. New techniques, such as quick-WES for the newborn in intensive care unit, direct-WGS for prenatal diagnosis and non-invasive test for fetal monogenic disorders, will become available in the near future.

Genetics for Healthcare Professionals

Genetics for Healthcare Professionals
Author: Heather Skirton,Christine Patch
Pages: 224
ISBN: 9781135325596
Available:
Release: 2013-02-01
Editor: Taylor & Francis
Language: en

Explanation of the Book:

Genetics is increasingly important in health care provision, but its relevance on a day-to-day basis is often poorly understood. Genetics for Healthcare Professionals introduces the general principles of genetics and links these to real world examples, to allow nurses, midwives, genetic counselors and doctors to apply this knowledge in their routine clinical practice. The book takes an holistic family-oriented approach, from preconception to adulthood, and addresses the misconception that clinical genetics is only of relevance to those who are reproducing. Genetics for Healthcare Professionals is an essential textbook of genetics for nurses, midwives, genetic counselors and doctors. An ideal coursebook for students in the healthcare professions, it is also written for qualified staff seeking an update on current issues and how to apply them in practice.

Genetics of Cardiomyopathy and Heart Failure An Issue of Heart Failure Clinics

Genetics of Cardiomyopathy and Heart Failure  An Issue of Heart Failure Clinics
Author: Calum MacRae
Pages: 157
ISBN: 9781455700356
Available:
Release: 2010-04-22
Editor: Elsevier Health Sciences
Language: en

Explanation of the Book:

This issue explores the genetic basis of specific cardiomyopathies and phenotypic components of heart failure with an eye to the clinical implications of this genetic knowledge. An understanding of the genetic causes of disease can aid in development of effective prevention and management strategies.

Genetic Counseling for Adult Neurogenetic Disease

Genetic Counseling for Adult Neurogenetic Disease
Author: Jill S. Goldman
Pages: 325
ISBN: 9781489974822
Available:
Release: 2014-12-01
Editor: Springer
Language: en

Explanation of the Book:

The adult patient diagnosed with or at risk for a neurogenetic disease has many questions and concerns for the genetic counselor, the neurologist, and other practitioners. Because of the emotional and potentially life-altering impact of these diseases on the patient and family, counseling can be especially challenging. A rare hands-on guide to the subject, Genetic Counseling for Adult Neurogenetic Disease deals with core issues that differentiate adult neurogenetic counseling from its more familiar pediatric counterpart. This innovative book with accompanying videos is designed to fill in deficits in this area typical of training programs in genetic counseling (which have pediatrics and prenatal concentrations) and neurology (which rarely cover genetic counseling). For each condition featured, chapters include a detailed overview of genetic symptoms, diagnostic criteria, and management, plus guidelines for asking, and answering, pertinent questions. The major concentration, however, is on genetic counseling issues and case histories illustrating these issues. As an added dimension, the accompanying videos depict representative issues and challenges in genetic counseling for specific diseases in addition to the basics of a neurological examination. Among the conditions discussed: Movement disorders, including Parkinson's disease. Dementias, including Alzheimer's disease. Stroke. Motor neuron diseases. Neuropathies and channelopathies. Adult muscular dystrophies. Neurocutaneous syndromes. Plus a section on neurological and neuropsychological evaluation. This is information that will stay relevant as technologies change and genetic understanding evolves. Genetic Counseling for Adult Neurogenetic Disease offers advanced clinical wisdom for genetic counselors as well as neurologists, neuropsychologists, and other referring clinicians.

The Gene Bomb

The Gene Bomb
Author: David E. Comings
Pages: 304
ISBN: 1878267396
Available:
Release: 1996
Editor: Hope Press
Language: en

Explanation of the Book:

Have you ever wondered by in recent years there seems to be an increase in the number of children and adults with attention deficit disorder, depression, learning disabilities, autism, and anxiety. Dr. Comings proposes a provocative new theory in which the delaying of childbearing in those with longer periods of education indirectly results in the selection of genes for these disorders.

The Gene Machine

The Gene Machine
Author: Bonnie Rochman
Pages: 288
ISBN: 9780374713966
Available:
Release: 2017-02-28
Editor: Scientific American / Farrar, Straus and Giroux
Language: en

Explanation of the Book:

A sharp-eyed exploration of the promise and peril of having children in an age of genetic tests and interventions Is screening for disease in an embryo a humane form of family planning or a slippery slope toward eugenics? Should doctors tell you that your infant daughter is genetically predisposed to breast cancer? If tests revealed that your toddler has a genetic mutation whose significance isn’t clear, would you want to know? In The Gene Machine, the award-winning journalist Bonnie Rochman deftly explores these hot-button questions, guiding us through the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family. Rochman tells the stories of scientists working to unlock the secrets of the human genome; genetic counselors and spiritual advisers guiding mothers and fathers through life-changing choices; and, of course, parents (including Rochman herself) grappling with revelations that are sometimes joyous, sometimes heartbreaking, but always profound. She navigates the dizzying and constantly expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, while considering how access to more tests is altering perceptions of disability and changing the conversation about what sort of life is worth living and who draws the line. Along the way, she highlights the most urgent ethical quandary: Is this technology a triumph of modern medicine or a Pandora’s box of possibilities? Propelled by human narratives and meticulously reported, The Gene Machine is both a scientific road map and a meditation on our power to shape the future. It is a book that gets to the very core of what it means to be human.